指南共识：常见恶性肿瘤联合筛查专家共识（2025版）

专家共识 肿瘤科 · 2025 · 肿瘤学杂志
恶性肿瘤联合筛查早诊早治共识

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陈可欣，陈万青，黄育北，等. 常见恶性肿瘤联合筛查专家共识（2025版）[J]. 中国肿瘤，2025，34（8）：583-610. CHEN K X， CHEN W Q， HUANG Y B，et al. Expert consensus on combined screening for common cancers（2025 Edition）[J]. China Cancer，2025，34（8）：583-610. 点击下载全文：常见恶性肿瘤联合筛查专家共识（2025版）.pdf ## 常见恶性肿瘤联合筛查专家共识（2025版） 作者：陈可欣1，陈万青2，黄育北1，吕章艳1，宋方方1，夏昌发2，许永杰2，杨雷3，盛超1，张雅聪1，王鹏1，张芸萌1，吉雨婷1，李净净1，李文轩1，吴婕1，金千韵1，宋丰举1 通信作者：陈可欣；陈万青 中国常见恶性肿瘤联合筛查专家共识制定专家组   中国常见恶性肿瘤联合筛查专家共识制定工作组 作者单位：1. 天津医科大学肿瘤医院流行病学研究室  国家肿瘤临床医学研究中心，天津 300060； 2. 国家癌症中心  国家肿瘤临床医学研究中心  中国医学科学院北京协和医学院肿瘤医院癌症早诊早治办公室，北京 100021； 3. 北京大学肿瘤医院内蒙古医院  内蒙古医科大学附属肿瘤医院  内蒙古癌症中心，内蒙古 呼和浩特 010020 基金项目：国家重点研发项目（2021YFC2500400） 摘   要：恶性肿瘤（或称癌症）是影响居民健康的重大公共卫生问题，造成严重的全球疾病负担。早期筛查能够大幅度提升恶性肿瘤的早诊早治，提高恶性肿瘤生存率。然而，当前恶性肿瘤筛查指南多只关注单一恶性肿瘤类型。通过科学合理的常见恶性肿瘤联合筛查，不仅能优化利用生物样本资源、提高受检者依从性、节省时间成本、提升恶性肿瘤筛查的全面性和有效性，同时有效降低筛查成本、合理配置医疗资源，减少恶性肿瘤综合疾病负担。常见恶性肿瘤联合筛查专家共识由中国抗癌协会肿瘤流行病学专业委员会发起，联合多学科专家，整合多种常见恶性肿瘤筛查与早诊早治领域的国内外研究进展，同时考虑中国国情和恶性肿瘤筛查的实际经验，根据世界卫生组织推荐的指南制定原则和方法完成证据评估。共识针对常见恶性肿瘤联合筛查过程中的筛查人群、技术和流程等给出了基于证据的推荐，旨在促进常见恶性肿瘤联合筛查与早诊早治效果，为中国的恶性肿瘤防控提供科学依据。 关键词：恶性肿瘤；联合筛查；早诊早治；共识 Expert Consensus on Combined Screening for Common Cancers（2025 Edition） CHEN Kexin1， CHEN Wanqing2， HUANG Yubei1， LYU Zhangyan1， SONG Fangfang1， XIA Changfa2， XU Yongjie2， YANG Lei3， SHENG Chao1， ZHANG Yacong1， WANG Peng1， ZHANG Yunmeng1， JI Yuting1， LI Jingjing1， LI Wenxuan1， WU Jie1， JIN Qianyun1， SONG Fengju1 Expert Group for the Expert Consensus on Combined Screening for Common Cancers in China， Working Group for the Expert Consensus on Combined Screening for Common Cancers in China （1. Department of Epidemiology， Tianjin Medical University Cancer Institute and Hospital/National Clinical Research Center for Cancer， Tianjin 300060， China； 2. National Cancer Center/National Clinical Research Center for Cancer/Office of Early Diagnosis and Early Treatment of Cancer， Cancer Hospital， Chinese Academy of Medical Sciences and Peking Union Medical College， Beijing 100021， China； 3. Peking University Cancer Hospital (Inner Mongolia Campus)/Affiliated Cancer Hospital of Inner Mongolia Medical University， Inner Mongolia Cancer Center， Hohhot 010020， China） Abstract： Malignant tumors(commonly referred to as cancer) represent a major global public health challenge and contribute significantly to the worldwide disease burden. Early screening plays a critical role in improving detection rates， enabling timely intervention， and enhancing patient survival rates. However， current cancer screening guidelines primarily focus on site-specific screening， which may not fully address the need for comprehensive early detection. A scientifically rational， multi-cancer screening approach offers several advantages： it optimizes the use of biological samples， reduces time costs for participants， enhances the efficiency and comprehensiveness of screening， and minimizes overall expenses. Such an approach also facilitates the rational allocation of healthcare resources， ultimately helping to reduce the societal burden of cancer. To address this need， the Cancer Epidemiology Committee of the Chinese Anti-Cancer Association has developed the Expert Consensus on Combined Screening for Common Cancers in China. This consensus integrates multidisciplinary expertise and synthesizes the latest domestic and international researches on cancer screening， early detection， and treatment for prevalent malignancies. Drawing upon China’s unique demographic and healthcare context， as well as practical screening experiences， the consensus provides evidence-based recommendations on target populations， screening technologies， and procedural workflows for multi-cancer screening. These guidelines align with the principles and methodologies established by the World Health Organization (WHO)， aiming to： enhance the effectiveness of combined cancer screening in China， improve early detection rates， and provide a scientific foundation for national cancer prevention and control strategies. Key words： malignant tumors； combined screening； early detection and treatment； consensus Volume 34 Number 8  2025

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肿瘤学杂志. 指南共识：常见恶性肿瘤联合筛查专家共识（2025版）[S/OL]. 2025.